Aromatic L- Amino Acid Decarboxylase Deficiency

National Dysautonomia Research Foundation
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Aromatic L- Amino Acid Decarboxylase Deficiency

Aromatic L- Amino Acid Decarboxylase Deficiency: an enzyme of the lyase class that catalyzes the decarboxylation of aromatic amino acids, notably converting dopa to dopamine, tryptophan to tryptamine, and hydroxytryptophan to serotonin. The enzyme is then bound to a pyridoxal phosphate cofactor and occurs particularly in the liver, kidney, brain, and vas deferens.

Clinical Presentation: symptoms may include temperature instability, ptosis of the eyelids, hypersalivation, distal chorea, swallowing difficulties, drowsiness, irritability, truncal hypotonia, oculogyric crises, pinpoint pupils.

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Aromatic L-Amino Acid Decarboxylase Deficiency (ALADD) Home Page www.aladd.com

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The National Dysautonomia Research Foundation (NDRF) has established this site to help inform afflicted patients, physicians and the general public on the various forms of Dysautonomia. It is our desire to give timely, as well as, accurate information, however NDRF will not be responsible for the misinterpretation of the information provided. Questions or problems regarding this web site should be directed to .

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